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Primary Pulmonary Hypertension

primary pulmonary hypertension

The symptoms of primary pulmonary hypertension can be mild, or they can be severe, depending on the progression of the disease. People suffering from pulmonary hypertension may feel short of breath during activity or lightheaded while at rest. These symptoms are normal in early stages and may be indicative of other diseases. In the case of patients with severe disease, lung transplantation may be an option. There are many different treatments for this condition. But the most effective treatment depends on the cause of the condition.

The underlying cause of primary pulmonary hypertension is not completely understood. Genetics and epigenetics have been implicated in some cases. Infection with HHV-8, for example, may contribute to the development of this disorder. It is also linked to certain medications. Some researchers have found evidence that the disease may be hereditary. This finding has been a boon for those undergoing treatment. However, more studies are needed to fully understand its etiology and determine the best treatment for each patient.

Other presenting symptoms of PH include anorexia, abdominal pain, and swelling, and cough and hemoptysis. While splenomegaly is rare, there are other causes of pulmonary hypertension, including schistosomiasis and portopulmonary hypertension. In the absence of specific symptoms, patients with PH often experience progressive pulmonary vascular resistance, worsening right ventricular function, and death.


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